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重组人 IL6 蛋白 (his-tag)

产品编号：XC983997-500μg 英文名称：Recombinant Human IL-6 Protein 中文名称：重组人 IL6 蛋白

商品名称：重组人 IL6 蛋白 (his-tag)

所属分类：

重组蛋白

电子邮箱：

taoweihong@constreambio.com

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产品参数

产品编号	XC983997-500μg
英文名称	Recombinant Human IL-6 Protein
中文名称	重组人 IL6 蛋白
别名	BSF2; HGF; HSF; IFNB2; IL6; Interleukin-6
Gene ID	3569
研究领域	Neuroinflammation
蛋白来源	Human
表达宿主	E. coli
蛋白标签	N-terminal 6xHis-tag
内毒素	<1 EU/mg as determined by TAL test
蛋白纯度	>95% purity by SDS-PAGE under reduced conditions
表达区域	Human IL-6 Protein is expressed from E. coli cells. It contains AA (Val 30 - Met 212) (Accession # P05231). This protein was fused with the His tag at the N-terminus
预测分子量	The protein has a calculated MW of 25kDa
缓冲液	0.2 μm filtered in PBS, pH 7.4, 50% glycerol

保存条件

Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍

Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing
the transition from innate to acquired immunity.