重组人 IL-15 蛋白 (his-tag)
- 商品名称： 重组人 IL-15 蛋白 (his-tag)
详情描述
- 产品描述
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产品参数
产品编号 XC982997-500μg 英文名称 Recombinant Human IL-15 Protein 中文名称 重组人IL-15 蛋白 别 名 IL15, Interleukin 15 Gene ID 3600 研究领域 Immunology 蛋白来源 Human 表达宿主 E. coli 蛋白标签 N-terminal 6xHis-tag 蛋白纯度 >95% purity by SDS-PAGE under reduced conditions. 表达区域 Human IL-15 Protein is expressed from E. coli cells. It contains AA （Asn 49 - Ser 162） (Accession # P40933), This protein was fused with the His tag at the N-terminus. 预测分子量 The protein has a calculated MW of 14.5 kDa 性 状 Liquid 缓冲液 0.2 μm filtered in PBS, pH 7.4, 50% glycerol 保存条件
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.
图片数据
SDS-PAGE 电泳
Lane M: Protein marker Lane 1: Reduced sample
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