重组人TNF-alpha 蛋白 (his-tag)
- 商品名称: 重组人TNF-alpha 蛋白 (his-tag)
详情描述
- 产品描述
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产品参数
产品编号 XC990997-500μg 英文名称 Recombinant Human TNF-alpha Protein 中文名称 重组人TNF-alpha 蛋白 别 名 DIF; TNF-alpha; TNFA; TNFSF2 Gene ID 7124 研究领域 Cancer Drug Targets 蛋白来源 Human 表达宿主 E. coli 蛋白标签 N-terminal 6xHis-tag 内毒素 <1 EU/mg as determined by TAL test 蛋白纯度 >95% purity by SDS-PAGE under reduced conditions. 表达区域 Human TNF-alpha Protein is expressed from E. coli cells. It contains AA (Val 77 - Leu 233) (Accession # P01375), This protein was fused with the His tag at the N-terminus . 预测分子量 The protein has a calculated MW of 20 kDa 性 状 Liquid 缓冲液 0.2 μm filtered in PBS, pH 7.4, 50% glycerol. 保存条件
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFAorTNFSF2, is the prototypic cytokine of the TNF superfamily, andisamultifunctional molecule involved in the regulation of a widespectrumofbiological processes including cell proliferation, differentiation, apoptosis,lipid metabolism, and coagulation. Two receptors, TNF-R1(TNFreceptortype 1; CD120a; p55/60) and TNF-R2 (TNF receptor type2; CD120b;p75/80), bind to TNF-alpha. TNF-alpha protein is producedmainlybymacrophages, and large amounts of this cytokine arereleasedinresponse to lipopolysaccharide, other bacterial products, andInterleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus,is regarded as a molecular insight in cancer treatment.
图片数据
SDS-PAGE 电泳
Lane M: Protein marker Lane 1: Reduced sample
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