重组小鼠 IL6 蛋白
- 商品名称: 重组小鼠 IL6 蛋白
详情描述
- 产品描述
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产品参数
产品编号 XC985997-500μg 英文名称 Recombinant Mouse IL6/Interleukin-6 Protein 中文名称 重组小鼠 IL6 蛋白 别 名 IL-6 Gene ID 16193 研究领域 Neuroinflammation 蛋白来源 Mouse 表达宿主 E. coli 蛋白标签 N-terminal 6xHis-tag 蛋白纯度 >95% purity by SDS-PAGE under reduced conditions. 表达区域 Mouse IL6 Protein is expressed from E. coli cells. It contains AA (Phe 25 - Thr 211) (Accession # P08505), This protein was fused with the His tag at the N-terminus. 预测分子量 The protein has a calculated MW of 26 kDa 性 状 Liquid 缓冲液 0.2 μm filtered in PBS, pH 7.4, 50% glycerol 保存条件
Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.
图片数据
SDS-PAGE 电泳
Lane M: Protein marker
Lane 1: Reduced sample
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