抗SN38单克隆抗体(Anti-SN38 mAb)

产品编号:XC992997 -100µg    英文名称:Anti-SN38 mAb    中文名称:抗SN38单克隆抗体   
  • 商品名称: 抗SN38单克隆抗体(Anti-SN38 mAb)

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详情描述

  • 产品描述
  • 产品参数

    产品编号XC992997 -100µg    
    英文名称Anti-SN38 mAb    
    中文名称抗SN38单克隆抗体    
    抗体来源Mouse    
    克隆类型Monoclonal    
    性   状Liquid    
    浓   度1mg/mL 
    亚   型IgG    
    表达系统Hybridoma    
    纯化方法affinity purified by Protein G 
    缓 冲 液0.2 μm filtered in PBS, pH 7.4    
    纯   度>95% as determined by SDS-PAGE;>98% as determined by SEC-HPLC    
    活   性EC50=0.08048 μg/mL by ELISA    
    应   用ELISA, Sandwich ELISA, Competitive ELISA    

    保存条件

    Aliquot and store at -20°C to -80°C,Avoid repeat freeze-thaw cycles.    

    注意事项

    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

    产品介绍

    SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is  a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage. Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38.

    图片数据

    SDS-PAGE    
    Anti-SN38 mAb on SDS-PAGE under reduced condition. The purity is 95.5%;     
    Anti-SN38  mAb on SDS-PAGE under non-reduced condition. The purity is 99.2%.

    SEC-HPLC    
    The purity of Anti-SN38 mAb is 100.0% as determined by SEC-HPLC. 

    ELISA Data    
    Dose response curve shows that the EC50 of Anti-SN38 mAb is 0.08048 μg/mL.

文件资料

图片名称

抗SN38单克隆抗体 COA

关键词:

对照药 | 抗药抗体 | 仪器 | 试剂

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